The ability to understand and empathize with others鈥� pain is grounded in cognitive neural processes rather than sensory ones, according to the results of a new study led by University of Colorado Boulder researchers.
The findings show that the act of perceiving others鈥� pain (i.e., empathy for others鈥� pain) does not appear to involve the same neural circuitry as experiencing pain in one鈥檚 own body, suggesting that they are different interactions within the brain.
鈥淭he research suggests that empathy is a deliberative process that requires taking another person鈥檚 perspective rather than being an instinctive, automatic process,鈥� said Tor Wager, the senior author of the study, director of the Cognitive and Affective Neuroscience Laboratory and Professor of Psychology and Neuroscience at 抖阴旅行射-Boulder.
was published online today in the journal eLife.
Empathy is a key cornerstone of human social behavior, but the complex neural interactions underlying this behavior are not yet fully understood. Previous hypotheses have suggested that the same brain regions that allow humans to feel pain in their own bodies might activate when perceiving the pain of others.
To test this idea, the researchers compared patterns of brain activity in human volunteers as they experienced moderate pain directly (via heat, shock, or pressure) in one experimental session, and watched images of others鈥� hands or feet being injured in another experimental session. When volunteers watched images, they were asked to try to imagine that the injuries were happening to their own bodies.
The researchers found that the brain patterns when the volunteers observed pain did not overlap with the brain patterns when the volunteers experienced pain themselves. Instead, while observing pain, the volunteers showed brain patterns consistent with mentalizing, which involves imagining another person鈥檚 thoughts and intentions.
The results suggest that within the brain, the experience of observing someone else in pain is neurologically distinct from that of experiencing physical pain oneself.
鈥淢ost previous studies focused only on the points of similarity between these two distinct experiences in a few isolated brain regions while ignoring dissimilarities. Our new study used a more granular analysis method,鈥� said Anjali Krishnan, the lead author of the study and a post-doctoral research associate in the Institute of Cognitive Science at 抖阴旅行射-Boulder while the research was conducted. She is currently an assistant professor at Brooklyn College of the City University of New York.
This new analysis method identified an empathy-predictive brain pattern that can be applied to new individuals to obtain a brain-related 鈥榲icarious pain score,鈥� opening new possibilities for measuring the strength of activity in brain systems that contribute to empathy.
The results may open new avenues of inquiry into how the brain regions involved in empathy help humans to relate to others when they experience different types of pain. Future studies may also explore the factors that influence one鈥檚 ability to adopt another鈥檚 perspective and whether it might be possible to improve this ability.
Co-authors of the new research include Choong-Wan Woo and Marina L贸pez-Sol脿 of 抖阴旅行射-Boulder; Luke Chang of Dartmouth College; Luka Ruzic of Duke University; Xiaosi Gu of the University of Texas at Dallas; Philip Jackson of Universit茅 Laval (Canada); Jes煤s Pujol of Hospital del Mar (Spain); and Jin Fan of Queens College of the City University of New York.
The National Institutes of Health (NIH) provided funding for the study.
Contact:
Tor Wager,听303-492-7487
tor.wager@colorado.edu
Anjali Krishnan, 972-922-9322
anjali.krishnan05@brooklyn.cuny.edu
Trent Knoss, 抖阴旅行射-Boulder media relations, 303-735-0528
trent.knoss@colorado.edu
A man's arm in a sling. Photo: Daniel Lobo / Flickr.
