aptamer

Small Molecule Regulation of CRISPR-Cas9 Using RNA Aptamers

June 24, 2020

Researchers at ¶¶ÒõÂÃÐÐÉä Boulder, led by Biochemistry Professor Robert Batey , have developed compositions and methods for temporal regulation of single guide RNAs (sgRNAs) that comprise a small molecule-binding aptamer in the sgRNA, which enables small-molecule-dependent gene editing in bacteria. They also developed a method for selecting sgRNAs that are...

celso espinoza

Biopharma Innovator: Celso Espinoza

June 22, 2020

Dr. Celso Espinoza is a senior drug discovery investigator with the biopharmaceutical firm AbbVie. Originally a component of Abbott Laboratories, AbbVie split in 2013 to focus on new drug discovery, and Celso followed. Since then, Celso has been a part of many major therapeutic breakthroughs including the immunosuppressor Humira, and...

Graycen Wheeler Portrait

Dealing with Adversity: Graycen Wheeler

June 5, 2020

Graycen Wheeler is a 6 th year graduate student in BCHM's Liu Lab. She was initially attracted to ¶¶ÒõÂÃÐÐÉä Biochem by the strong web presence and diversity of research in the department’s labs. During graduate recruitment, “the interview process wasn’t nearly as anxiety-inducing and I felt natural interacting with grad...

Photo of BCHM grad student Otto Kletzein

RNA and Beyond: Otto Kletzien

June 5, 2020

Otto Kletzien likes to stay busy. He’s a Signaling and Cellular Regulation (SCR) fellow, one of approximately 15 in the department, an active participant and former leader of ¶¶ÒõÂÃÐÐÉä Boulder’s RNA Club chapter, for which he ran operations and finance, a contributor to the Synthetic Biology Journal Club, and he’s...

Yannick Thumbnail

The Curious Scientist: Yannick Lee-yow

May 27, 2020

Local Roots First up in our Be a Biochemist series is undergraduate Yannick Lee-yow, a Biochemistry (BCHM) and Molecular, Cellular, and Developmental Biology (MCDB) double major who had a round-about path into biochemistry. He found a home conducting independent research with MCDB’s Dr. Ding Xue for the past four years...

bacteria

Scientists shed light on essential carbon-fixing machinery in bacteria

May 6, 2020

Scientists have been studying cyanobacteria and its many potential applications for decades, from cutting CO2 emissions to creating a substitute for oil-based plastics, but there wasn’t a deep understanding of the full life cycle and metabolism of specialized compartments within these common bacteria – until now.

mcbride family

Key coronavirus testing technology has ¶¶ÒõÂÃÐÐÉä Boulder tie

April 6, 2020

Alumnus worked in lab of Distinguished Professor Marvin Caruthers assisting in the development of pioneering technology

sabrina spencer

To divide or not to divide? The mother cell may decide

April 2, 2020

When do cells decide to divide? For 40 years, the textbook answer has been that this decision occurs in the first phase of a cell’s existence – right after a mother cell divides to become daughter cells. But researchers at ¶¶ÒõÂÃÐÐÉä Boulder have found that it’s actually the mother cell...

cyanobacteria photosynthesis

Even single-celled organisms need their space: Squished bacteria may shut down photosynthesis

March 23, 2020

In a study published today, a team at ¶¶ÒõÂÃÐÐÉä Boulder took advantage of a new microscopic technique to follow the lives of individual bacteria as they grew and divided in complex colonies.

Mo Gordon

Mo Gordon Wins 2020 SRAA Outstanding Poster Award

March 6, 2020

Moshe Gordon, a Biochemistry graduate student in Dr. Joseph Falke's lab has been awarded the SRAA Outstanding Poster Award at the 2020 Biophysical Society Annual Conference in San Diego, California. Moshe presented his poster, titled "Single-Molecule Diffusion Studies of Membrane-bound PDK1-PKC Heterodimers Reveal a Monomee-Dimer Equilibrium with Regulatory Significance," during...

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